The thermodynamics analysis of steam power plant is a topic of fundamental interest to Mechanical Engineering and Energy Engineering disciplines. Classically, the course on “Power Plant Engineering” is most popular in the engineering colleges of the country where only steam power cycle and its subsequent execution of power generation from steam are addressed. In this backdrop, the new the course on “Power Plant System Engineering” is proposed with advanced topics on power generation mechanisms from various energy resources. It covers fundamental aspects steam generation mechanisms (such as boilers, re-heaters, super-heaters), steam power generation units (impulse and reaction turbines), condensing units and cooling towers. With recent crises of fuel (coal) and stringent emission norms, the steam power system is normally integrated with gas power cycles through cogeneration mode of power generation. So, few contents of the course are emphasized towards gas power system. In addition, fundamental theories of power generation from non-conventional and renewable energy system are a recent inclusion in this course. The course contents are explained in simplified and lucid manner for beginners of intended audience. The scientists and practicing engineers of R&D organizations and public sector undertakings, will gain the fundamental glimpses on working principles and thermodynamic aspects of power plants. The syllabus is framed with respect to guidelines of “Mechanical/Energy Engineering” AICTE approved UG course curriculum. The methodical online teaching, problem solving approach and online evaluation will help the candidate for credit transfer for their course curriculum.